India is one of the few countries in the world in which polio has not yet been eradicated. A recent campaign in India to vaccinate more people was launched last month, and in just five days, 2 and 1/2 million workers vaccinated over 178 million children. This article describes the struggle to fight polio in India. In addition, polio is still endemic in Afghanistan, Pakistan, and Nigeria, while other cases appear in other countries periodically. This website describes the Global Polio Eradication Initiative and provides weekly updates on cases of polio and vaccination efforts worldwide. In addition, due to polio’s remaining prevalence in Asia, the United States recently signed a Protocol of Intent on Cooperation for the Global Eradication of Polio, to help fight what remains of this crippling disease. This editorial tells more about this agreement. It will be interesting to follow the efforts to eradicate this disease and see how countries work together to spread the vaccination to areas that still remain without access to proper healthcare.